FRS3 and CBY2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FRS3	CBY2
Description		fibroblast growth factor receptor substrate 3	chibby family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Cytoplasmic Vesicle
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	MAPK Cascade Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway
Pathways		FRS-mediated FGFR1 signaling FRS-mediated FGFR2 signaling FRS-mediated FGFR3 signaling FRS-mediated FGFR4 signaling RAF/MAP kinase cascade Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870)
Interacting Genes		28 interacting genes: ADAMTSL4 BMPR2 CBY2 DDX5 FGFR1 GATA1 GRB14 GRB2 KARS1 MAPK1 MATK NOTCH2NLA NTRK1 NTRK2 NUMB PLSCR1 PRKCI PTPN11 RFX6 RND1 SH2B1 SOCS6 SPRY2 TCF4 TLE5 TNS1 TRIP6 VASP	76 interacting genes: ACTN1 ARHGEF40 ARMC7 C19orf44 C1orf109 CCDC146 CCDC198 CCHCR1 CCNG1 CDC23 CDK2 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 DGCR6 DUSP14 DZIP1L EIF4E2 ELOA ENKD1 FAM161A FANCG FRS3 GADD45A GOLGA2 GOLGA6L2 GRAP2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NINL NTAQ1 PID1 PIN1 PLEKHN1 POLR1C PPP1R18 PRPF31 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SYCE1 TCEANC TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655 ZNF688
Entrez ID		10817	220082
HPRD ID		06373	14856
Ensembl ID		ENSG00000137218	ENSG00000174015
Uniprot IDs		A0A140VJJ7 O43559	A0A140VJV5 Q8NA61
PDB IDs		2KUP 2KUQ 2YS5 2YT2
Enriched GO Terms of Interacting Partners?
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