CELF1 and TOM1L1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CELF1	TOM1L1
Description		CUGBP Elav-like family member 1	target of myb1 like 1 membrane trafficking protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding BRE Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching RNA Interference Negative Regulation Of Translation Regulation Of RNA Splicing	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 24162737) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body mass index ( 28552196) Estimated glomerular filtration rate ( 30604766) Global electrical heterogeneity phenotypes ( 29622589) Glomerular filtration rate ( 29403010) Hand grip strength ( 29691431) Immature fraction of reticulocytes ( 27863252) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Metabolic syndrome ( 31589552) Neuroticism ( 29255261) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Sleep duration (short sleep) ( 30846698) Total cholesterol levels ( 30275531) Type 2 diabetes ( 30297969)	Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965)
Interacting Genes		7 interacting genes: APP DMPK FUBP1 HNRNPC PPBP RALY TOM1L1	28 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP
Entrez ID		10658	10040
HPRD ID		03046	05266
Ensembl ID		ENSG00000149187	ENSG00000141198
Uniprot IDs		G5EA30 Q92879	O75674 Q8NI65
PDB IDs		2CPZ 2DHS 2RQ4 2RQC 3NMR 3NNA 3NNC 3NNH	3RRU
Enriched GO Terms of Interacting Partners?
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