TOM1L1 and TOLLIP

Number of citations of the paper that reports this interaction (PubMedID 15047686)
46

Data Source:
HPRD (in vitro)

		TOM1L1	TOLLIP
Description		target of myb1 like 1 membrane trafficking protein	toll interacting protein
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Extracellular Exosome	Extracellular Region Cytoplasm Cytosol Nuclear Body Azurophil Granule Lumen Specific Granule Lumen Interleukin-18 Receptor Complex Interleukin-1 Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Cell-cell Signaling Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Intracellular Signal Transduction Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway
Pathways			Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965)	Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		28 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	44 interacting genes: ACTN2 ATXN1 BHLHE40 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DZIP3 EIF2AK2 FTH1 GGA1 GGA2 GGA3 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 LDB1 N4BP2 NTAQ1 ODAM PEG10 PRR20A RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 TBX3 TLR2 TLR4 TOM1 TOM1L1 UBC WBP2 WRNIP1 XRN2 ZBTB16 ZHX1
Entrez ID		10040	54472
HPRD ID		05266	05887
Ensembl ID		ENSG00000141198	ENSG00000078902
Uniprot IDs		O75674 Q8NI65	B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2
PDB IDs		3RRU	1WGL 2N31
Enriched GO Terms of Interacting Partners?
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