CELF1 and PPBP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CELF1	PPBP
Description		CUGBP Elav-like family member 1	pro-platelet basic protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding BRE Binding	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching RNA Interference Negative Regulation Of Translation Regulation Of RNA Splicing	Platelet Degranulation Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Leukocyte Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport
Pathways			Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic Acid Copper
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 24162737) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body mass index ( 28552196) Estimated glomerular filtration rate ( 30604766) Global electrical heterogeneity phenotypes ( 29622589) Glomerular filtration rate ( 29403010) Hand grip strength ( 29691431) Immature fraction of reticulocytes ( 27863252) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Metabolic syndrome ( 31589552) Neuroticism ( 29255261) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Sleep duration (short sleep) ( 30846698) Total cholesterol levels ( 30275531) Type 2 diabetes ( 30297969)	Metabolite levels ( 22916037)
Interacting Genes		7 interacting genes: APP DMPK FUBP1 HNRNPC PPBP RALY TOM1L1	20 interacting genes: CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		10658	5473
HPRD ID		03046	07171
Ensembl ID		ENSG00000149187	ENSG00000163736
Uniprot IDs		G5EA30 Q92879	P02775
PDB IDs		2CPZ 2DHS 2RQ4 2RQC 3NMR 3NNA 3NNC 3NNH	1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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