DRAP1 and FOXH1

Number of citations of the paper that reports this interaction (PubMedID 12471260)
24

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro, in vivo)

		DRAP1	FOXH1
Description		DR1 associated protein 1	forkhead box H1
Image
GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Activin Responsive Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Enhancer Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding SMAD Binding Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Heart Looping Secondary Heart Field Specification Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Pathways		Signaling by NODAL Signaling by Activin	Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988) General cognitive ability ( 29844566)
Interacting Genes		26 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX2 NCK2 NFYB PIK3R3 PLEKHF2 POLE3 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	7 interacting genes: DRAP1 FOXG1 NKX2-5 SMAD2 SMAD3 SMAD4 SOX4
Entrez ID		10589	8928
HPRD ID		03796	04689
Ensembl ID		ENSG00000175550	ENSG00000160973
Uniprot IDs		Q14919	O75593
PDB IDs		1JFI	5XOC
Enriched GO Terms of Interacting Partners?
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