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DRAP1 and TBP
Number of citations of the paper that reports this interaction (PubMedID
11461703
)
49
Data Source:
HPRD
(in vivo, in vitro)
DRAP1
TBP
Description
DR1 associated protein 1
TATA-box binding protein
Image
GO Annotations
Cellular Component
Nucleus
Transcription Factor TFIIIB Complex
Nuclear Chromatin
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Transcription Factor Complex
Transcription Factor TFIID Complex
Transcription Factor TFIIA Complex
Nuclear Euchromatin
Cytoplasm
Protein-containing Complex
Transcriptional Preinitiation Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Identical Protein Binding
Protein Heterodimerization Activity
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Proximal Promoter Sequence-specific DNA Binding
RNA Polymerase III General Transcription Initiation Factor Activity
RNA Polymerase III Regulatory Region DNA Binding
Core Promoter Binding
TFIIB-class Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Aryl Hydrocarbon Receptor Binding
Enzyme Binding
Transcription Regulatory Region DNA Binding
Repressing Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription By RNA Polymerase III
Spermatogenesis
Viral Process
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
RNA Polymerase II Preinitiation Complex Assembly
RNA Polymerase III Preinitiation Complex Assembly
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Signaling by NODAL
Signaling by Activin
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Acne (severe) (
24927181
)
Eosinophil percentage of granulocytes (
27863252
)
Multiple sclerosis (
31604244
)
Neutrophil percentage of granulocytes (
27863252
)
Severe influenza A (H1N1) infection (
26379185
)
Type 1 diabetes (
21980299
)
Interacting Genes
26 interacting genes:
APP
ARHGEF10L
CDKN2C
DNAJB11
DR1
FBXO7
FEZ1
FEZ2
FOXH1
GTF2B
LMO2
LNX2
NCK2
NFYB
PIK3R3
PLEKHF2
POLE3
SDCBP
SRPK2
TAF9
TAF9B
TBP
TK1
TNFRSF14
TTF2
ZEB1
120 interacting genes:
ABT1
AHR
AR
ATF4
BCL3
BRD2
BRF1
BRF2
BTAF1
CAND2
CEP43
CITED2
COL26A1
CREG1
CREM
CTBP1
CTCFL
CXXC1
DHX9
DR1
DRAP1
E2F1
EDF1
ELF3
ESR1
ETS1
FATE1
FOS
FOXF2
GOLGA2
GTF2A1
GTF2A1L
GTF2A2
GTF2B
GTF2E1
GTF2E2
GTF2F1
GTF2F2
GTF2H4
GTF3C2
GTF3C3
GTF3C4
GTF3C5
H3-4
HAP1
HMGB1
HNF4A
HNRNPK
HSF1
HTT
HUWE1
IKZF1
JUN
JUND
JUP
KDM5A
KLF5
MBD2
MCM2
MDM2
MSX1
MYC
NACA
NCAPH
NCOA1
NCOA3
NCOA6
NFYB
NFYC
NR3C1
PAX3
PAX5
PAX6
PIAS1
PIAS3
POLR2A
POLR3F
POU2F1
POU2F2
POU3F2
PSMC2
RB1
REL
RELA
REST
RNF4
RUVBL1
RUVBL2
RXRA
SERPINB5
SNAPC1
SNAPC2
SNAPC4
SP1
SPI1
SPIB
SSX2IP
SUB1
TAF1
TAF10
TAF11
TAF12
TAF13
TAF1A
TAF1B
TAF1C
TAF1L
TAF5
TAF7L
TCF12
TEAD1
TP53
TRAM2
TRIP4
UBE2I
UBTF
WDR62
YEATS2
YWHAE
ZNF76
Entrez ID
10589
6908
HPRD ID
03796
02511
Ensembl ID
ENSG00000175550
ENSG00000112592
Uniprot IDs
Q14919
P20226
Q32MN7
PDB IDs
1JFI
1C9B
1CDW
1JFI
1NVP
1TGH
4ROC
4ROD
4ROE
5FUR
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5N9G
6MZD
6MZL
6MZM
6O9L
Enriched GO Terms of Interacting Partners
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