TACC3 and TBC1D22B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TACC3	TBC1D22B
Description		transforming acidic coiled-coil containing protein 3	TBC1 domain family member 22B
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding 14-3-3 Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Bladder cancer ( 24163127 20972438) Urinary bladder cancer ( 20348956)	Acne (severe) ( 24927181) Platelet count ( 27863252)
Interacting Genes		16 interacting genes: AKAP9 ARNT ARNT2 ASPSCR1 AURKA CIB3 CLIP4 EIF3C KAT2A KIZ NDEL1 NOD2 SNX20 TBC1D22B TTF2 VPS37C	23 interacting genes: CALCOCO2 CCDC57 CDR2 DAPK1 DEUP1 FXR2 GOLGA2 HSD17B14 IKZF3 KRT40 LRRK2 MFHAS1 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52
Entrez ID		10460	55633
HPRD ID		05601	15475
Ensembl ID		ENSG00000013810	ENSG00000065491
Uniprot IDs		Q9Y6A5	Q9NU19
PDB IDs		5LXN 5LXO 5ODS 5ODT	6D0S
Enriched GO Terms of Interacting Partners?
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