TBC1D22B and HSD17B14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TBC1D22B	HSD17B14
Description		TBC1 domain family member 22B	hydroxysteroid 17-beta dehydrogenase 14
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GO Annotations	Cellular Component		Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding 14-3-3 Protein Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly	Estrogen Biosynthetic Process Steroid Catabolic Process Oxidation-reduction Process
Pathways			Estrogen biosynthesis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Platelet count ( 27863252)	Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		23 interacting genes: CALCOCO2 CCDC57 CDR2 DAPK1 DEUP1 FXR2 GOLGA2 HSD17B14 IKZF3 KRT40 LRRK2 MFHAS1 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52	16 interacting genes: CA8 CDKN2D CYTOR DDIT3 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B
Entrez ID		55633	51171
HPRD ID		15475	16801
Ensembl ID		ENSG00000065491	ENSG00000087076
Uniprot IDs		Q9NU19	A0A140VJH8 Q9BPX1
PDB IDs		6D0S	1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO
Enriched GO Terms of Interacting Partners?
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