TBC1D22B and VPS52

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TBC1D22B	VPS52
Description		TBC1 domain family member 22B	VPS52 subunit of GARP complex
Image			No pdb structure
GO Annotations	Cellular Component		GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding 14-3-3 Protein Binding	Protein Binding Rab GTPase Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Platelet count ( 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		23 interacting genes: CALCOCO2 CCDC57 CDR2 DAPK1 DEUP1 FXR2 GOLGA2 HSD17B14 IKZF3 KRT40 LRRK2 MFHAS1 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52	50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2
Entrez ID		55633	6293
HPRD ID		15475	09142
Ensembl ID		ENSG00000065491	ENSG00000223501
Uniprot IDs		Q9NU19	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs		6D0S
Enriched GO Terms of Interacting Partners?
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