HMG20B and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMG20B	CCDC136
Description		high mobility group 20B	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Body	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways		HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		20 interacting genes: APP BRCA2 CCDC102B CCDC136 CCDC85B E2F6 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 PHF21A SYCE1 TACC2 TFIP11 TRAF1 VIM	64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26
Entrez ID		10362	64753
HPRD ID		05703	10887
Ensembl ID		ENSG00000064961	ENSG00000128596
Uniprot IDs		Q9P0W2	A0A024R758 Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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