HMG20B and HNRNPL

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HMG20B	HNRNPL
Description		high mobility group 20B	heterogeneous nuclear ribonucleoprotein L
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Body	Nucleus Nucleoplasm Cytosol Membrane Ribonucleoprotein Granule Pronucleus Perinuclear Region Of Cytoplasm Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	DNA Binding Protein Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Transcription Regulatory Region DNA Binding Pre-mRNA Intronic Binding MRNA CDS Binding
	Biological Process	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Regulation Of Translation Circadian Rhythm RNA Metabolic Process Cellular Response To Amino Acid Starvation Regulation Of RNA Splicing Positive Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Response To Peptide Positive Regulation Of MRNA Binding
Pathways		HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs			Copper
Diseases
GWAS			Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		20 interacting genes: APP BRCA2 CCDC102B CCDC136 CCDC85B E2F6 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 PHF21A SYCE1 TACC2 TFIP11 TRAF1 VIM	16 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH NEDD4 PCBP2 PJA1 PTBP1 SUMO4
Entrez ID		10362	3191
HPRD ID		05703	04360
Ensembl ID		ENSG00000064961	ENSG00000104824
Uniprot IDs		Q9P0W2	P14866 Q6NTA2
PDB IDs			3R27 3TO8
Enriched GO Terms of Interacting Partners?
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