PTPRU and IRS1

  • Number of citations of the paper that reports this interaction (PubMedID 11781100)
  • 9
  • Data Source:
  • BioGRID (enzymatic study)

PTPRU

IRS1

Description protein tyrosine phosphatase receptor type U insulin receptor substrate 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder and schizophrenia ( 20889312)
  • Blood protein levels ( 30072576)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Pediatric non-alcoholic fatty liver disease activity score ( 23535911)
  • Schizophrenia ( 28991256)
  • Tourette syndrome ( 30818990)
Interacting Genes 10 interacting genes: CTNNB1 EGFR ERBB2 GNAI1 GNAI2 GNAI3 GNAO1 IRS1 KIT PPFIA3 78 interacting genes: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK3 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 NUMB PASK PDPK1 PELI1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRD PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBC UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 10076 3667
HPRD ID 03908 00943
Ensembl ID ENSG00000060656 ENSG00000169047
Uniprot IDs Q92729 P35568
PDB IDs 1IRS 1K3A 1QQG 2Z8C 5U1M 6BNT
Enriched GO Terms of Interacting Partners?
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