PTPRU and PPFIA3

Number of citations of the paper that reports this interaction (PubMedID 9624153)
84

Data Source:
HPRD (in vitro)

		PTPRU	PPFIA3
Description		protein tyrosine phosphatase receptor type U	PTPRF interacting protein alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Beta-catenin Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Negative Regulation Of Cell Proliferation Cell Differentiation Negative Regulation Of Cell Migration Animal Organ Regeneration Homotypic Cell-cell Adhesion Protein Localization To Cell Surface Peptidyl-tyrosine Dephosphorylation Response To Glucocorticoid Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin	Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization
Pathways		Signaling by SCF-KIT	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Bipolar disorder and schizophrenia ( 20889312) Blood protein levels ( 30072576) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Pediatric non-alcoholic fatty liver disease activity score ( 23535911) Schizophrenia ( 28991256) Tourette syndrome ( 30818990)
Interacting Genes		10 interacting genes: CTNNB1 EGFR ERBB2 GNAI1 GNAI2 GNAI3 GNAO1 IRS1 KIT PPFIA3	11 interacting genes: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS PTPRU
Entrez ID		10076	8541
HPRD ID		03908	04393
Ensembl ID		ENSG00000060656	ENSG00000177380
Uniprot IDs		Q92729	O75145
PDB IDs
Enriched GO Terms of Interacting Partners?
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