AP1M2 and AP1M1

Number of citations of the paper that reports this interaction (PubMedID 10535737)
184

Data Source:
HPRD (in vivo)

		AP1M2	AP1M1
Description		adaptor related protein complex 1 subunit mu 2	adaptor related protein complex 1 subunit mu 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cell Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Targeting Vesicle Targeting Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2	47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A
Entrez ID		10053	8907
HPRD ID		06296	04639
Ensembl ID		ENSG00000129354	ENSG00000072958
Uniprot IDs		Q53GI5 Q9Y6Q5	A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?
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