AP1M1 and LAMP1

Number of citations of the paper that reports this interaction (PubMedID 7569928)
331

Data Source:
HPRD (in vitro, two hybrid)

		AP1M1	LAMP1
Description		adaptor related protein complex 1 subunit mu 1	lysosomal associated membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Late Endosome Membrane Azurophil Granule Membrane Sarcolemma Melanosome Neuronal Cell Body Cytolytic Granule Autolysosome Perinuclear Region Of Cytoplasm Phagolysosome Membrane Extracellular Exosome Alveolar Lamellar Body Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Virus Receptor Activity Protein Binding Enzyme Binding Protein Domain Specific Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus	Granzyme-mediated Apoptotic Signaling Pathway Neutrophil Degranulation Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Autophagic Cell Death Protein Stabilization Establishment Of Protein Localization To Organelle Golgi To Lysosome Transport Regulation Of Organelle Transport Along Microtubule
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Neutrophil degranulation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A	2 interacting genes: AP1M1 AP2M1
Entrez ID		8907	3916
HPRD ID		04639	01076
Ensembl ID		ENSG00000072958	ENSG00000185896
Uniprot IDs		A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5	A0A024RDY3 P11279
PDB IDs
Enriched GO Terms of Interacting Partners?
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