AP1M2 and AP1S1

Number of citations of the paper that reports this interaction (PubMedID 10535737)
184

Data Source:
HPRD (in vivo)

		AP1M2	AP1S1
Description		adaptor related protein complex 1 subunit mu 2	adaptor related protein complex 1 subunit sigma 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cell Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Terminal Bouton Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding
	Biological Process	Protein Targeting Vesicle Targeting Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Retrograde Transport, Endosome To Golgi Regulation Of Defense Response To Virus By Virus
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2	5 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 RHOU
Entrez ID		10053	1174
HPRD ID		06296	04635
Ensembl ID		ENSG00000129354	ENSG00000106367
Uniprot IDs		Q53GI5 Q9Y6Q5	A0A024QYT6 P61966
PDB IDs			4P6Z
Enriched GO Terms of Interacting Partners?
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