AP1M1 and VANGL2

Number of citations of the paper that reports this interaction (PubMedID 23326640)
32

Data Source:
BioGRID (pull down, two hybrid)

		AP1M1	VANGL2
Description		adaptor related protein complex 1 subunit mu 1	VANGL planar cell polarity protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome	Stress Fiber Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane COPII-coated ER To Golgi Transport Vesicle Cell Pole
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Heart Looping Membranous Septum Morphogenesis Muscular Septum Morphogenesis Planar Cell Polarity Pathway Involved In Axis Elongation Rho Protein Signal Transduction Anterior/posterior Pattern Specification Heparan Sulfate Proteoglycan Biosynthetic Process Convergent Extension Involved In Neural Plate Elongation Regulation Of Wnt Signaling Pathway Glomerulus Development Regulation Of Actin Cytoskeleton Organization Somatic Stem Cell Population Maintenance Cell Migration Involved In Kidney Development Post-anal Tail Morphogenesis Dopaminergic Neuron Axon Guidance Serotonergic Neuron Axon Guidance Wound Healing Positive Regulation Of JUN Kinase Activity Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Somatic Stem Cell Division Establishment Of Body Hair Planar Orientation Digestive Tract Morphogenesis Convergent Extension Involved In Axis Elongation Inner Ear Receptor Cell Stereocilium Organization Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Lateral Sprouting Involved In Lung Morphogenesis Kidney Morphogenesis Planar Cell Polarity Pathway Involved In Heart Morphogenesis Cochlea Morphogenesis Establishment Of Planar Polarity Involved In Neural Tube Closure Planar Cell Polarity Pathway Involved In Neural Tube Closure Planar Cell Polarity Pathway Involved In Axon Guidance Non-motile Cilium Assembly
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	PCP/CE pathway Asymmetric localization of PCP proteins
Drugs
Diseases
GWAS			Cognitive performance ( 19734545) Multiple sclerosis ( 31604244 24076602) Systemic lupus erythematosus ( 28714469)
Interacting Genes		47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A	5 interacting genes: AP1M1 ARFRP1 DVL1 MAGI3 SQSTM1
Entrez ID		8907	57216
HPRD ID		04639	02758
Ensembl ID		ENSG00000072958	ENSG00000162738
Uniprot IDs		A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5	A8K4L6 Q9ULK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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