AP1M1 and ZBTB43

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AP1M1	ZBTB43
Description		adaptor related protein complex 1 subunit mu 1	zinc finger and BTB domain containing 43
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome	Nuclear Chromatin
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus	Regulation Of Transcription By RNA Polymerase II
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS			BMI (adjusted for smoking behaviour) ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Eyebrow thickness ( 26926045)
Interacting Genes		47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A	19 interacting genes: AEN AP1M1 ARR3 ARRB1 BDP1 DIP2A ELOA2 FAM161A LMO1 LMO3 LMO4 LNX1 MCM10 MORF4L2 PSMD3 SYT6 TRAF2 ZBTB24 ZNF417
Entrez ID		8907	23099
HPRD ID		04639	08346
Ensembl ID		ENSG00000072958	ENSG00000169155
Uniprot IDs		A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5	O43298
PDB IDs			2CSH
Enriched GO Terms of Interacting Partners?
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