TOLLIP and PRR20A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TOLLIP	PRR20A
Description		toll interacting protein	proline rich 20A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Nuclear Body Azurophil Granule Lumen Specific Granule Lumen Interleukin-18 Receptor Complex Interleukin-1 Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Cell-cell Signaling Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Intracellular Signal Transduction Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway
Pathways		Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS		Idiopathic pulmonary fibrosis ( 24429156)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Systolic blood pressure ( 30224653)
Interacting Genes		44 interacting genes: ACTN2 ATXN1 BHLHE40 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DZIP3 EIF2AK2 FTH1 GGA1 GGA2 GGA3 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 LDB1 N4BP2 NTAQ1 ODAM PEG10 PRR20A RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 TBX3 TLR2 TLR4 TOM1 TOM1L1 UBC WBP2 WRNIP1 XRN2 ZBTB16 ZHX1	26 interacting genes: ATXN1 BANP C1orf94 DAB1 DAZAP2 FAM168A FOXP3 GATA2 NAA38 NCK2 NEDD9 PITX1 POGZ RBFOX1 RBM10 RBPMS ROR2 SELENOV SIAH1 SOX5 SP4 THAP1 TOLLIP VAC14 ZC3H10 ZNF488
Entrez ID		54472	122183
HPRD ID		05887	13445
Ensembl ID		ENSG00000078902	ENSG00000204919
Uniprot IDs		B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2	P86478 P86479 P86480 P86481 P86496
PDB IDs		1WGL 2N31
Enriched GO Terms of Interacting Partners?
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