TOLLIP and RHOXF2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		TOLLIP	RHOXF2
Description		toll interacting protein	Rhox homeobox family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Nuclear Body Azurophil Granule Lumen Specific Granule Lumen Interleukin-18 Receptor Complex Interleukin-1 Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Exosome	Nuclear Chromatin Nucleus
	Molecular Function	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Cell-cell Signaling Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Intracellular Signal Transduction Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways		Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS		Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		44 interacting genes: ACTN2 ATXN1 BHLHE40 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DZIP3 EIF2AK2 FTH1 GGA1 GGA2 GGA3 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 LDB1 N4BP2 NTAQ1 ODAM PEG10 PRR20A RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 TBX3 TLR2 TLR4 TOM1 TOM1L1 UBC WBP2 WRNIP1 XRN2 ZBTB16 ZHX1	58 interacting genes: ARID5A ARMCX2 ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TENT5B TENT5C TENT5D TLE5 TMCC2 TOLLIP TRIP13 UBE2I UPF1 UTP6 VAC14 VPS25 ZBTB32
Entrez ID		54472	84528
HPRD ID		05887	02345
Ensembl ID		ENSG00000078902	ENSG00000131721
Uniprot IDs		B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2	Q9BQY4
PDB IDs		1WGL 2N31
Enriched GO Terms of Interacting Partners?
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