NEK2 and NDC80

  • Number of citations of the paper that reports this interaction (PMID 12386167)
  • 27
  • Data Source:
  • BioGRID (two hybrid, two hybrid)
  • HPRD (in vitro, two hybrid, in vivo)

NEK2

NDC80

Gene Name NIMA-related kinase 2 NDC80 kinetochore complex component
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 23 interactors: CCDC85A CEP250 CHGA CSN2 CTNNB1 DCTN1 EDRF1 EIF4A2 GIT1 IFT140 IMMT MAD1L1 MAPK1 MCC NDC80 NEK11 PDE4DIP PPP1CA PPP1CC PPP1R2 SPTBN4 TCF25 TPM3 45 interactors: AMOTL2 ATF4 ATP5O AURKA AURKB BLOC1S6 CALCOCO1 CCDC101 CCDC53 CCHCR1 CCNH CCNK CENPH HAUS1 HGS IFT20 INPP1 KLC3 KLHL12 KRT6B MAD1L1 MAD2L1 MED4 MFAP1 MIS12 NDE1 NDEL1 NEK2 NUF2 PFDN1 PSMC2 RB1 RUFY4 SFR1 SKA1 SMC1A SPC25 STX11 TFIP11 TNIP1 TOM1L1 TP53BP2 TXLNA USHBP1 ZWINT
Entrez ID 4751 10403
HPRD ID 04953 06277
Ensembl ID ENSG00000117650 ENSG00000080986
Uniprot IDs P51955 A8K031 O14777
PDB IDs 2JAV 2W5A 2W5B 2W5H 2WQO 2XK3 2XK4 2XK6 2XK7 2XK8 2XKC 2XKD 2XKE 2XKF 2XNM 2XNN 2XNO 2XNP 4A4X 4AFE 2IGP 2VE7 3IZ0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
called  complementary  cyclins  dissociated  dnas  ectopic  elucidate  eventually  g2  gst  hec  heptad  hydrolyzes  inhibits  interacts  leucine  mitosis  mitotic  modulate  mss1  p45  proteasome  proteolysis  pull  repeats  seventh  smc1  smc2  telophase 
assembled  ccan  cenh3  cenp  centromere  centromeres  centromeric  continues  deposition  egg  entails  exit  immunoprecipitate  interphase  kinetochore  kinetochores  mis12  mitosis  orchestrate  precedes  propagation  reconstituted  segregation  sixteen  soon  spite  vertebrate  w  xenopus 
Tagcloud (Difference) ?
called  complementary  cyclins  dissociated  dnas  ectopic  elucidate  eventually  g2  gst  hec  heptad  hydrolyzes  inhibits  interacts  leucine  mitotic  modulate  mss1  p45  proteasome  proteolysis  pull  repeats  seventh  smc1  smc2  telophase 
assembled  ccan  cenh3  cenp  centromere  centromeres  centromeric  continues  deposition  egg  entails  exit  immunoprecipitate  interphase  kinetochore  kinetochores  mis12  orchestrate  precedes  propagation  reconstituted  segregation  sixteen  soon  spite  vertebrate  w  xenopus 
Tagcloud (Intersection) ?
mitosis