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KHDRBS1 and SASH1
Number of citations of the paper that reports this interaction (PMID
22745667
)
1
Data Source:
BioGRID
(unspecified method)
KHDRBS1
SASH1
Gene Name
KH domain containing, RNA binding, signal transduction associated 1
SAM and SH3 domain containing 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Grb2-Sos Complex
Membrane
Protein Complex
Molecular Function
DNA Binding
RNA Binding
SH3/SH2 Adaptor Activity
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Protein C-terminus Binding
Protein Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Complex Scaffold
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Transcription, DNA-templated
MRNA Processing
Cell Cycle Arrest
Signal Transduction
Cell Surface Receptor Signaling Pathway
Cell Proliferation
Positive Regulation Of Signal Transduction
Regulation Of Protein Stability
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Protein Polyubiquitination
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Angiogenesis
Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of NIK/NF-kappaB Signaling
Regulation Of Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease (
20061627
)
Protein quantitative trait loci (
18464913
)
Thyroid hormone levels (
23408906
)
Type 2 diabetes nephropathy (
21150874
)
Protein-Protein Interactions
109 interactors:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
BZRAP1
CBL
CD2AP
CDK1
CIRBP
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
EFEMP1
EMG1
FGR
FNBP4
FRK
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MIA2
MPP6
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OSTF1
PACSIN1
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RBMX
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SSFA2
STAT3
STUB1
TBL1X
TJP1
TNFSF11
TUBB3
U2AF2
UBA52
UBASH3B
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
2 interactors:
KHDRBS1
SKIL
Entrez ID
10657
23328
HPRD ID
03926
06408
Ensembl ID
ENSG00000121774
ENSG00000111961
Uniprot IDs
Q07666
O94885
PDB IDs
2XA6
3QHE
2DL0
2EBP
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Fc Receptor Signaling Pathway
Signaling
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Communication
Peptidyl-tyrosine Autophosphorylation
Innate Immune Response
Signal Transduction
Immune Response-regulating Signaling Pathway
Immune Response
Endocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Locomotion
Movement Of Cell Or Subcellular Component
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Cell Surface Receptor Signaling Pathway
Defense Response
Positive Regulation Of Immune Response
Regulation Of Immune System Process
Cellular Response To Peptide Hormone Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Phagocytosis
Cellular Response To Peptide
Positive Regulation Of Immune System Process
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Immune Response
Epidermal Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Growth Factor
Antigen Receptor-mediated Signaling Pathway
Cell Differentiation
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Cellular Component Organization
Immune System Process
Response To Stimulus
Regulation Of Signaling
Cell Projection Organization
Intracellular Signal Transduction
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Cell Cycle Arrest
Positive Regulation Of RNA Export From Nucleus
Negative Regulation Of Cell Cycle
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Heterotrimerization
Regulation Of RNA Export From Nucleus
Positive Regulation Of Translational Initiation
Protein Homotrimerization
Regulation Of Cell Cycle
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Cell Cycle Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Lens Fiber Cell Differentiation
Protein Trimerization
Positive Regulation Of Signal Transduction
Negative Regulation Of Gene Expression
Blastocyst Formation
Negative Regulation Of Biosynthetic Process
Cell Cycle
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Response To Antibiotic
Positive Regulation Of Response To DNA Damage Stimulus
Lymphocyte Homeostasis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Translational Initiation
Positive Regulation Of Translation
Positive Regulation Of Axonogenesis
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Leukocyte Homeostasis
Negative Regulation Of Cellular Metabolic Process
Lens Development In Camera-type Eye
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Blastocyst Development
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Nucleocytoplasmic Transport
Transcription, DNA-templated
G2/M Transition Of Mitotic Cell Cycle
RNA Biosynthetic Process
Regulation Of Response To DNA Damage Stimulus
Protein Heterooligomerization
Skeletal Muscle Tissue Development
Transforming Growth Factor Beta Receptor Signaling Pathway
Skeletal Muscle Organ Development
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Axonogenesis
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Tagcloud
?
adjacent
analyse
aza
cpg
degree
deoxycytidine
elevation
follows
g2
hep
hepatocellular
liver
massarray
methylation
particularly
pattern
pcr
possibly
promoter
propose
quantitative
real
relationship
repressed
rt
shared
sites
strongly
tissues
Tagcloud (Difference)
?
adjacent
analyse
aza
cpg
degree
deoxycytidine
elevation
follows
g2
hep
hepatocellular
liver
massarray
methylation
particularly
pattern
pcr
possibly
promoter
propose
quantitative
real
relationship
repressed
rt
shared
sites
strongly
tissues
Tagcloud (Intersection)
?