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KHDRBS1 and FGR
Number of citations of the paper that reports this interaction (PMID
15190072
)
16
Data Source:
BioGRID
(unspecified method, enzymatic study)
KHDRBS1
FGR
Gene Name
KH domain containing, RNA binding, signal transduction associated 1
FGR proto-oncogene, Src family tyrosine kinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Grb2-Sos Complex
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Cytosol
Cytoskeleton
Plasma Membrane
Actin Cytoskeleton
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
RNA Binding
SH3/SH2 Adaptor Activity
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Phosphotyrosine Binding
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Immunoglobulin Receptor Binding
Fc-gamma Receptor I Complex Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Transcription, DNA-templated
MRNA Processing
Cell Cycle Arrest
Signal Transduction
Cell Surface Receptor Signaling Pathway
Cell Proliferation
Positive Regulation Of Signal Transduction
Regulation Of Protein Stability
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Blood Coagulation
Regulation Of Cell Shape
Response To Virus
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Cell Migration
Peptidyl-tyrosine Phosphorylation
Cell Differentiation
Positive Regulation Of Cell Migration
Peptidyl-tyrosine Autophosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of Cell Proliferation
Positive Regulation Of Mast Cell Degranulation
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Innate Immune Response
Regulation Of Innate Immune Response
Regulation Of Protein Kinase Activity
Protein Autophosphorylation
Positive Regulation Of Cytokine Secretion
Regulation Of Phagocytosis
Defense Response To Gram-positive Bacterium
Cellular Response To Peptide Hormone Stimulus
Pathways
Platelet homeostasis
Platelet sensitization by LDL
Fcgamma receptor (FCGR) dependent phagocytosis
FCGR activation
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
109 interactors:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
BZRAP1
CBL
CD2AP
CDK1
CIRBP
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
EFEMP1
EMG1
FGR
FNBP4
FRK
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MIA2
MPP6
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OSTF1
PACSIN1
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RBMX
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SSFA2
STAT3
STUB1
TBL1X
TJP1
TNFSF11
TUBB3
U2AF2
UBA52
UBASH3B
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
22 interactors:
ARRB1
CBL
CCR3
CSK
DAB2
DOK1
ERBB2
FASLG
HCLS1
IKBKG
INPP5D
KHDRBS1
NR1I2
PTK2
SLAMF1
SNCA
SRC
STAT3
SYK
VDR
WAS
YWHAQ
Entrez ID
10657
2268
HPRD ID
03926
01288
Ensembl ID
ENSG00000121774
ENSG00000000938
Uniprot IDs
Q07666
P09769
P78453
PDB IDs
2XA6
3QHE
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Fc Receptor Signaling Pathway
Signaling
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Communication
Peptidyl-tyrosine Autophosphorylation
Innate Immune Response
Signal Transduction
Immune Response-regulating Signaling Pathway
Immune Response
Endocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Locomotion
Movement Of Cell Or Subcellular Component
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Cell Surface Receptor Signaling Pathway
Defense Response
Positive Regulation Of Immune Response
Regulation Of Immune System Process
Cellular Response To Peptide Hormone Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Phagocytosis
Cellular Response To Peptide
Positive Regulation Of Immune System Process
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Immune Response
Epidermal Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Growth Factor
Antigen Receptor-mediated Signaling Pathway
Cell Differentiation
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Cellular Component Organization
Immune System Process
Response To Stimulus
Regulation Of Signaling
Cell Projection Organization
Intracellular Signal Transduction
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Signaling
Cell Communication
Positive Regulation Of Signal Transduction
Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Signal Transduction
Response To Stimulus
Regulation Of Cell Death
Positive Regulation Of Protein Metabolic Process
Response To Organic Substance
Regulation Of Endocytosis
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Protein Phosphorylation
Cell Surface Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Apoptotic Process
Cellular Response To Organic Substance
Regulation Of Cell Proliferation
Positive Regulation Of Phosphorylation
Regulation Of Cellular Component Organization
Positive Regulation Of Protein Modification Process
Regulation Of Tissue Remodeling
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Intracellular Transport
Positive Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Cellular Metabolic Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Immune Response-regulating Signaling Pathway
Immune System Process
Positive Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Transport
Regulation Of Metabolic Process
Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transferase Activity
Regulation Of Catalytic Activity
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Bone Resorption
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
colocalization
confocal
edge
electrophoretic
fyn
hck
incompletely
isre
jak
jak1
jak3
lyn
masses
migrating
mobility
p59
plasminogen
polarization
ptk
ptks
src
stat1
supershift
tyk2
upa
upar
urokinase
utilizes
vsmc
Tagcloud (Difference)
?
colocalization
confocal
edge
electrophoretic
fyn
hck
incompletely
isre
jak
jak1
jak3
lyn
masses
migrating
mobility
p59
plasminogen
polarization
ptk
ptks
src
stat1
supershift
tyk2
upa
upar
urokinase
utilizes
vsmc
Tagcloud (Intersection)
?