SASH1

Gene Name		SAM and SH3 domain containing 1
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Gene Ontology Annotations	Cellular Component	Membrane Protein Complex
	Molecular Function	Protein C-terminus Binding Protein Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Complex Scaffold
	Biological Process	Protein Polyubiquitination Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of JUN Kinase Activity Positive Regulation Of Angiogenesis Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of P38MAPK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 20061627) Protein quantitative trait loci ( 18464913) Thyroid hormone levels ( 23408906) Type 2 diabetes nephropathy ( 21150874)
Protein-protein Interactions		2 interactors: KHDRBS1 SKIL
Entrez ID		23328
HPRD ID		06408
Ensembl ID		ENSG00000111961
Uniprot IDs		O94885
PDB IDs		2DL0 2EBP
Enriched GO Terms of Interacting Partners?		Cell Cycle Arrest Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Heterotrimerization Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Protein Homotrimerization Regulation Of Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Lens Fiber Cell Differentiation Protein Trimerization Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Blastocyst Formation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Antibiotic Positive Regulation Of Response To DNA Damage Stimulus Lymphocyte Homeostasis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Translational Initiation Positive Regulation Of Translation Positive Regulation Of Axonogenesis Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Leukocyte Homeostasis Negative Regulation Of Cellular Metabolic Process Lens Development In Camera-type Eye Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Blastocyst Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated G2/M Transition Of Mitotic Cell Cycle RNA Biosynthetic Process Regulation Of Response To DNA Damage Stimulus Protein Heterooligomerization Skeletal Muscle Tissue Development Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Organ Development Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Tagcloud ?		adjacent analyse aza cpg degree deoxycytidine elevation follows g2 hep hepatocellular liver massarray methylation particularly pattern pcr possibly promoter propose quantitative real relationship repressed rt shared sites strongly tissues