NR1I3 and DEDD

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NR1I3	DEDD
Description		nuclear receptor subfamily 1 group I member 3	death effector domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton	Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Apoptotic Process
Pathways
Drugs		Doxylamine Meclizine Loperamide Ketoconazole Atorvastatin Pheniramine Prasterone 16,17-Androstene-3-Ol Resveratrol Cholesterol Phenolphthalein 3,20-Pregnanedione Hexestrol Triclosan
Diseases
GWAS		Blood metabolite levels ( 24816252)
Interacting Genes		18 interacting genes: CHD9 DNMT3L FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC	16 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 KRT18 KRT8 SHMT1 SMAD3
Entrez ID		9970	9191
HPRD ID		04858	06022
Ensembl ID		ENSG00000143257	ENSG00000158796
Uniprot IDs		F1DAL4 Q14994	B1AQP5 O75618
PDB IDs		1XV9 1XVP
Enriched GO Terms of Interacting Partners?
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