FAM20B and BSCL2

Data Source:
BioGRID (two hybrid)

		FAM20B	BSCL2
Description		FAM20B glycosaminoglycan xylosylkinase	BSCL2 lipid droplet biogenesis associated, seipin
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Golgi Apparatus Integral Component Of Membrane	Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding ATP Binding Kinase Activity Phosphotransferase Activity, Alcohol Group As Acceptor Metal Ion Binding	Protein Binding Phospholipid Binding
	Biological Process	Protein Phosphorylation Proteoglycan Biosynthetic Process	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis Lipid Droplet Formation
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS			Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: BSCL2 FAM209A FFAR2 GPR152 KCNJ6 SLC7A14 TIMMDC1 TMEM80	38 interacting genes: ANKRD46 B4GALNT2 BMP10 CLDN19 CMTM7 CPEB2 CXCL9 CYSRT1 ERMP1 FAM20B GABARAPL1 GMCL1 HOXA1 KRTAP6-3 LAT MALL NSG1 OLFM4 PLEKHF2 PLIN1 RPRM SERP1 SERP2 SFTPC SMIM3 SMLR1 STRIT1 TEX37 TMEM19 TMEM218 TMEM222 TRAM1L1 TRARG1 TRIM54 TSPAN2 UPK2 USE1 VAMP3
Entrez ID		9917	26580
HPRD ID		13297	05858
Ensembl ID		ENSG00000116199	ENSG00000168000
Uniprot IDs		A0A024R918 O75063	A0A024R540 A0A024R549 Q96G97
PDB IDs			6DS5
Enriched GO Terms of Interacting Partners?
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