AP5Z1 and NUP93

Data Source:
BioGRID (two hybrid)

		AP5Z1	NUP93
Description		adaptor related protein complex 5 subunit zeta 1	nucleoporin 93
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck AP-type Membrane Coat Adaptor Complex AP-5 Adaptor Complex	Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Nuclear Periphery Host Cell
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Double-strand Break Repair Via Homologous Recombination Protein Transport Endosomal Transport	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Nuclear Envelope Organization Viral Process Protein Sumoylation Poly(A)+ MRNA Export From Nucleus Viral Transcription Nuclear Pore Complex Assembly Positive Regulation Of SMAD Protein Signal Transduction SMAD Protein Signal Transduction Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Parental extreme longevity (95 years and older) ( 27015805)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Gambling ( 22780124) HDL cholesterol ( 20031564) HDL cholesterol levels ( 32203549 26763881) Potassium levels ( 29403010)
Interacting Genes		2 interacting genes: MDFI NUP93	7 interacting genes: AP5Z1 MPPED2 NDC1 NUP205 OPCML PLA2G6 TMEM100
Entrez ID		9907	9688
HPRD ID		13801	14854
Ensembl ID		ENSG00000242802	ENSG00000102900
Uniprot IDs		O43299	Q8N1F7
PDB IDs			5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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