SNAP91 and NECAP1

Data Source:
HPRD (in vivo)

		SNAP91	NECAP1
Description		synaptosome associated protein 91	NECAP endocytosis associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Clathrin-coated Pit Synaptic Vesicle Clathrin-coated Vesicle Extrinsic Component Of Presynaptic Endocytic Zone Membrane	Cytosol Clathrin-coated Pit Clathrin Vesicle Coat
	Molecular Function	SNARE Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Kinase Binding Clathrin Heavy Chain Binding	Protein Binding
	Biological Process	Vesicle Budding From Membrane Protein Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Clathrin Coat Assembly Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis	Endocytosis Protein Transport Vesicle-mediated Transport Membrane Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Electrodermal activity ( 25387706) Macular thickness ( 30535121) Refractive error ( 32231278) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		15 interacting genes: ABI2 AP2A2 AP2B1 DNAJC5 EPS15 ERBB2 ERBB3 ERBB4 GEM MIPOL1 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B	9 interacting genes: AMPH AP1B1 APP DAB2 DAPK1 DNAJC5 HIP1 REL SNAP91
Entrez ID		9892	25977
HPRD ID		06391	14819
Ensembl ID		ENSG00000065609	ENSG00000089818
Uniprot IDs		B7Z2N2 E9PDG8 O60641	Q8NC96
PDB IDs			6RH5 6RH6
Enriched GO Terms of Interacting Partners?
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