NUAK1 and MRPS25

Data Source:
BioGRID (affinity chromatography technology)

		NUAK1	MRPS25
Description		NUAK family kinase 1	mitochondrial ribosomal protein S25
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton	Mitochondrion Mitochondrial Inner Membrane Ribosome
	Molecular Function	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Structural Constituent Of Ribosome
	Biological Process	Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Cell Adhesion Regulation Of Myosin-light-chain-phosphatase Activity Intracellular Signal Transduction Regulation Of Cell Population Proliferation Cellular Response To Glucose Starvation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Regulation of TP53 Activity through Phosphorylation	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs		Fostamatinib
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831) Attention function in attention deficit hyperactive disorder ( 26174813) Brain morphology (MOSTest) ( 32665545) General glucose level in pregnancy (gestational week 30-32) ( 30324795) Lateral ventricular volume in normal aging ( 30258056) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Two-hour glucose in pregnancy (gestational week 30-32) ( 30324795)
Interacting Genes		5 interacting genes: APP CASP6 FBXO25 LATS1 PPP1CC	1 interacting genes: ERCC6
Entrez ID		9891	64432
HPRD ID		12171	17594
Ensembl ID		ENSG00000074590	ENSG00000131368
Uniprot IDs		A0A024RBL3 O60285	P82663
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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