PPP1R26 and UTP20

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		PPP1R26	UTP20
Description		protein phosphatase 1 regulatory subunit 26	UTP20 small subunit processome component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleoplasm Nucleolus Cytoplasm Plasma Membrane 90S Preribosome Preribosome, Small Subunit Precursor Small-subunit Processome
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Negative Regulation Of Cell Population Proliferation
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Alcohol dependence (age at onset) ( 24962325) Brain structure (hippocampal volume) ( 20197096) Health literacy ( 31250787)
Interacting Genes		5 interacting genes: HOOK2 PPP1CA RB1 TRIB3 UTP20	72 interacting genes: MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PPP1R26
Entrez ID		9858	27340
HPRD ID		11099	09928
Ensembl ID		ENSG00000196422	ENSG00000120800
Uniprot IDs		Q5T8A7	O75691
PDB IDs
Enriched GO Terms of Interacting Partners?
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