KIAA0319 and FEM1B

Data Source:
HPRD (two hybrid)

		KIAA0319	FEM1B
Description		KIAA0319	fem-1 homolog B
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GO Annotations	Cellular Component	Early Endosome Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Death Receptor Binding Protein Binding
	Biological Process	Neuron Migration Response To Auditory Stimulus Negative Regulation Of Axon Extension Multicellular Organismal Response To Stress Negative Regulation Of Axon Extension Involved In Regeneration Positive Regulation Of SMAD Protein Signal Transduction Membrane Organization Negative Regulation Of Dendrite Development	Apoptotic Process Protein Ubiquitination Post-translational Protein Modification Regulation Of Ubiquitin-protein Transferase Activity Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of DNA Damage Checkpoint
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neddylation
Drugs
Diseases
GWAS		Radiation response ( 20923822) Serum uric acid levels ( 30993211) Waist-to-hip ratio adjusted for BMI ( 28552196)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Major depressive disorder ( 23377640) Systolic blood pressure ( 26969751)
Interacting Genes		3 interacting genes: APP FEM1B SH2B1	7 interacting genes: APAF1 FAS GLI1 KIAA0319 NKX3-1 PPM1F RAD9A
Entrez ID		9856	10116
HPRD ID		18713	16889
Ensembl ID		ENSG00000137261	ENSG00000169018
Uniprot IDs		A0A087X0U9 Q5VV43	Q9UK73
PDB IDs		2E7M	6LBF 7CNG
Enriched GO Terms of Interacting Partners?
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