CDA and ZNF598

Data Source:
HPRD (two hybrid)

		CDA	ZNF598
Description		cytidine deaminase	zinc finger protein 598, E3 ubiquitin ligase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity	RNA Binding Protein Binding Ribosome Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process	Protein Monoubiquitination Protein Ubiquitination Rescue Of Stalled Ribosome
Pathways		Neutrophil degranulation Pyrimidine salvage
Drugs		1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598	3 interacting genes: CDA DBN1 UBE2D1
Entrez ID		978	90850
HPRD ID		11744	11732
Ensembl ID		ENSG00000158825	ENSG00000167962
Uniprot IDs		P32320	Q86UK7
PDB IDs		1MQ0
Enriched GO Terms of Interacting Partners?
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