TBC1D5 and CHIA

Data Source:
BioGRID (two hybrid)

		TBC1D5	CHIA
Description		TBC1 domain family member 5	chitinase acidic
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GO Annotations	Cellular Component	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding	Chitinase Activity Protein Binding Chitin Binding Kinase Binding
	Biological Process	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly	Polysaccharide Catabolic Process Immune System Process Production Of Molecular Mediator Involved In Inflammatory Response Chitin Metabolic Process Chitin Catabolic Process Apoptotic Process Positive Regulation Of Chemokine Production Polysaccharide Digestion
Pathways			Digestion of dietary carbohydrate
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 32888494 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Parkinson's disease ( 32201043) Platelet count ( 32888494 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 32888494 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Anti-Toxoplasma gondii IgG seropositivity ( 30610941) Interferon alpha levels in systemic lupus erythematosus ( 25338677) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: AP2M1 ATXN1 CHIA EIF1AD FBXL7 GABARAPL1 GABARAPL2 MAP1LC3A UBC ZBTB25	3 interacting genes: COX20 RBBP8NL TBC1D5
Entrez ID		9779	27159
HPRD ID		10262	09355
Ensembl ID		ENSG00000131374	ENSG00000134216
Uniprot IDs		B9A6K1 Q92609	A8K3T7 Q1M0P3 Q1M0P4 Q2VT96 Q9BZP6
PDB IDs		5GTU	2YBT 2YBU 3FXY 3FY1 3RM4 3RM8 3RM9 3RME
Enriched GO Terms of Interacting Partners?
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