CHIA and TBC1D5

Data Source:
BioGRID (two hybrid)

		CHIA	TBC1D5
Description		chitinase acidic	TBC1 domain family member 5
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex
	Molecular Function	Chitinase Activity Protein Binding Chitin Binding Kinase Binding	GTPase Activator Activity Protein Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Polysaccharide Catabolic Process Immune System Process Production Of Molecular Mediator Involved In Inflammatory Response Chitin Metabolic Process Chitin Catabolic Process Apoptotic Process Positive Regulation Of Chemokine Production Polysaccharide Digestion	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Digestion of dietary carbohydrate
Drugs
Diseases
GWAS		Anti-Toxoplasma gondii IgG seropositivity ( 30610941) Interferon alpha levels in systemic lupus erythematosus ( 25338677) Metabolite levels ( 23823483)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 32888494 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Parkinson's disease ( 32201043) Platelet count ( 32888494 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 32888494 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: COX20 RBBP8NL TBC1D5	10 interacting genes: AP2M1 ATXN1 CHIA EIF1AD FBXL7 GABARAPL1 GABARAPL2 MAP1LC3A UBC ZBTB25
Entrez ID		27159	9779
HPRD ID		09355	10262
Ensembl ID		ENSG00000134216	ENSG00000131374
Uniprot IDs		A8K3T7 Q1M0P3 Q1M0P4 Q2VT96 Q9BZP6	B9A6K1 Q92609
PDB IDs		2YBT 2YBU 3FXY 3FY1 3RM4 3RM8 3RM9 3RME	5GTU
Enriched GO Terms of Interacting Partners?
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