KMT2B and SEPTIN8

Data Source:
BioGRID (two hybrid)

		KMT2B	SEPTIN8
Description		lysine methyltransferase 2B	septin 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex	Septin Ring Microtubule Cytoskeleton Axon Synaptic Vesicle Membrane Septin Complex Cell Division Site Presynapse
	Molecular Function	Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Unmethylated CpG Binding	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Histone H3-K4 Dimethylation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K4 Monomethylation	Cellular Protein Localization Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Eosinophil percentage of white cells ( 32888494) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ANXA1 ANXA7 ASH2L ATP1B1 ATXN1 CDKN1A GRB7 H3C1 H3C14 MTDH NREP PIK3R3 PIN1 PRPF40A RAP1B RBBP5 RCC1 RPP14 SEPTIN8 SMAD3 SMARCB1 SMN1 TK1 TRIM55 TRIM63 TSC22D1 ZNF512B	11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1
Entrez ID		9757	23176
HPRD ID		06017	12228
Ensembl ID		ENSG00000272333	ENSG00000164402
Uniprot IDs		Q9UMN6	A6NFQ9 B7ZVZ1 Q92599
PDB IDs		3UVM 4ERZ 4PZI 7BRE	6UPR
Enriched GO Terms of Interacting Partners?
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