CD79B and FOXJ1

Data Source:
BioGRID (pull down)

		CD79B	FOXJ1
Description		CD79b molecule	forkhead box J1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane B Cell Receptor Complex Extracellular Exosome	Chromatin Nucleus
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Signal Transduction B Cell Differentiation B Cell Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Actin Cytoskeleton Organization Ciliary Basal Body Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Cellular Protein Localization Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Activation Of GTPase Activity Positive Regulation Of Lung Ciliated Cell Differentiation
Pathways		CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs		Polatuzumab vedotin
Diseases		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Height ( 25282103)
Interacting Genes		14 interacting genes: BLK CD19 CD3E CD5 CD79A FYN LCK LYN PTK2 PTPN6 SGTA SGTB SYK ZAP70	8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2
Entrez ID		974	2302
HPRD ID		00922	03798
Ensembl ID		ENSG00000007312	ENSG00000129654
Uniprot IDs		P40259	A0A024R8P1 Q92949
PDB IDs		3KG5
Enriched GO Terms of Interacting Partners?
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