RAB11FIP3 and ARF6

Data Source:
HPRD (in vitro)

		RAB11FIP3	ARF6
Description		RAB11 family interacting protein 3	ADP ribosylation factor 6
Image
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane	Ruffle Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Filopodium Membrane Early Endosome Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Exosome Flemming Body Presynapse Glutamatergic Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Thioesterase Binding Protein N-terminus Binding
	Biological Process	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion	Liver Development Intracellular Protein Transport Cell Cycle Cell Adhesion Nervous System Development Vesicle-mediated Transport Cell Differentiation Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Endocytic Recycling Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Positive Regulation Of Protein Secretion Cell Division Regulation Of Filopodium Assembly Positive Regulation Of Keratinocyte Migration Regulation Of Dendritic Spine Development Establishment Of Epithelial Cell Polarity Ruffle Assembly Hepatocyte Apoptotic Process Maintenance Of Postsynaptic Density Structure Positive Regulation Of Focal Adhesion Disassembly Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Presynapse Assembly Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Dendrite Development
Pathways		VxPx cargo-targeting to cilium	TBC/RABGAPs Clathrin-mediated endocytosis MET receptor recycling
Drugs			5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate Myristic acid
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)	Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34	37 interacting genes: AGAP1 AP1B1 AP3B1 AP3D1 AP3S2 APBB1 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR HTR2A IKBKG ITSN1 MEOX2 MT2A PALS1 PIP5K1A PIP5K1C PLD1 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 SMAP1 SPAG9 ZNF709
Entrez ID		9727	382
HPRD ID		18521	02714
Ensembl ID		ENSG00000090565	ENSG00000165527
Uniprot IDs		O75154	P62330
PDB IDs		2D7C 2HV8 4D0M 4UJ3 4UJ4	1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ 6PAU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?