NOS1AP and RASD1

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		NOS1AP	RASD1
Description		nitric oxide synthase 1 adaptor protein	ras related dexamethasone induced 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Caveola Z Disc T-tubule Nuclear Membrane Sarcoplasmic Reticulum Membrane Sarcolemma Perinuclear Region Of Cytoplasm Glutamatergic Synapse Inward Rectifier Potassium Channel Complex L-type Voltage-gated Calcium Channel Complex	Nucleus Plasma Membrane Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Nitric-oxide Synthase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Gene Expression Positive Regulation Of Nitric Oxide Mediated Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Cardiac Muscle Cell Action Potential Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Positive Regulation Of Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Positive Regulation Of Peptidyl-cysteine S-nitrosylation	Signal Transduction G Protein-coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Body mass index (change over time) ( 25133637) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732 20062061 20062063 25055868) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Iris color (L* coordinate) ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Long QT syndrome ( 32429735) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Mosquito bite size ( 28199695) Obesity-related traits ( 23251661) QT interval ( 23166209 30679814 20031603 29213071 16648850 24952745 22726844 19305408 19305409 19587794 29874175) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) T wave morphology restitution during exercise ( 31607149) T wave morphology restitution during exercise (MTAG) ( 31607149) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Word reading ( 23738518)	Chronotype ( 30696823) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600)
Interacting Genes		20 interacting genes: AKNAD1 APP CKM CT45A5 FAM133A FYN HSPD1 LRP1 LRP2 LRP8 NHP2 NOS1 PLAGL2 PNP RASD1 RYBP SYN1 SYN2 SYN3 TRAF4	37 interacting genes: ABI2 BHLHE41 CCDC57 CDR2L CYSRT1 EXOSC8 GNAI1 GNAI2 GNB1 HNRNPK HNRNPR KHDRBS3 KRT34 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-9 KRTAP6-2 KRTAP6-3 MATR3 MDFI MKRN3 MTUS2 NBPF19 NOS1 NOS1AP NOTCH2NLA PLSCR1 PRDM5 PTPN21 RASAL3 RBMY1A1 RBMY1F RBMY1J TRIM37 WWP2
Entrez ID		9722	51655
HPRD ID		12023	08958
Ensembl ID		ENSG00000198929	ENSG00000108551
Uniprot IDs		O75052	Q9Y272
PDB IDs
Enriched GO Terms of Interacting Partners?
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