SOX13 and YTHDC1

Data Source:
BioGRID (two hybrid)

		SOX13	YTHDC1
Description		SRY-box transcription factor 13	YTH domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Spinal Cord Oligodendrocyte Cell Differentiation Gamma-delta T Cell Differentiation Cell Fate Commitment Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ziprazidone in schizophrenia ( 29503163) Thyroid stimulating hormone levels ( 30843173)	Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: CTBP2 INO80B SMAD7 TRAF2 TXLNB VEZF1 YTHDC1 ZNF587	42 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 MPRIP PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		9580	91746
HPRD ID		09205	11689
Ensembl ID		ENSG00000143842	ENSG00000083896
Uniprot IDs		Q9UN79	J3QR07 Q96MU7
PDB IDs			2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9
Enriched GO Terms of Interacting Partners?
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