CIR1 and DPPA4

Data Source:
BioGRID (two hybrid)

		CIR1	DPPA4
Description		corepressor interacting with RBPJ, CIR1	developmental pluripotency associated 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Nuclear Speck Protein-containing Complex	Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Kinase Binding Histone Deacetylase Binding Protein-containing Complex Binding	Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development
Pathways			POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525) Adult body size ( 32376654) Chronotype ( 30696823) Hand grip strength ( 29691431) Triglyceride levels ( 32203549)	Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: CCDC33 CEP76 DPPA4 HDAC2 MB21D2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1	35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID		9541	55211
HPRD ID		05568	16836
Ensembl ID		ENSG00000138433	ENSG00000121570
Uniprot IDs		Q86X95	Q7L190
PDB IDs		6ZYM
Enriched GO Terms of Interacting Partners?
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