STXBP5L and STX12

Data Source:
BioGRID (two hybrid)

		STXBP5L	STX12
Description		syntaxin binding protein 5 like	syntaxin 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane SNARE Complex Neuromuscular Junction Neuronal Dense Core Vesicle	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	GTPase Activator Activity Protein Binding Syntaxin Binding Myosin II Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Glucose Homeostasis Positive Regulation Of GTPase Activity Negative Regulation Of Insulin Secretion Regulation Of Protein Secretion Regulation Of Synaptic Vesicle Exocytosis	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways
Drugs
Diseases
GWAS		Aging (facial) ( 23223146) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Paracentral lobule volume ( 31530798) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482) Response to lurasidone in schizophrenia ( 29730043)
Interacting Genes		3 interacting genes: GPSM3 STX12 STX2	43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		9515	23673
HPRD ID		19367	06059
Ensembl ID		ENSG00000145087	ENSG00000117758
Uniprot IDs		B4DKF6 E9PFI2 Q9Y2K9	Q86Y82
PDB IDs			2DNX
Enriched GO Terms of Interacting Partners?
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