PMPCB and ARPC1B

Data Source:
BioGRID (genetic interference)

		PMPCB	ARPC1B
Description		peptidase, mitochondrial processing subunit beta	actin related protein 2/3 complex subunit 1B
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Tubulobulbar Complex Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Metal Ion Binding	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Response To Estradiol Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Response To Estrogen Ephrin Receptor Signaling Pathway
Pathways		Mitochondrial protein import Processing of SMDT1	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Diverticular disease ( 30177863)	Alcohol consumption ( 31358974) Facial emotion recognition (sad faces) ( 28608620) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944)
Interacting Genes		5 interacting genes: FXN MARK3 NPSR1 PMPCA PTGER4	10 interacting genes: ACTB ACTR2 APP ARPC2 ARPC4 ARPC5 AURKA PAK1 SRPK2 WAS
Entrez ID		9512	10095
HPRD ID		07539	10366
Ensembl ID		ENSG00000105819	ENSG00000130429
Uniprot IDs		B3KM34 O75439 Q96CP5	A4D275 O15143
PDB IDs			6UHC 6YW6
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?