CABP1 and PPP3R1

Data Source:
BioGRID (pull down)

		CABP1	PPP3R1
Description		calcium binding protein 1	protein phosphatase 3 regulatory subunit B, alpha
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Perinuclear Region Of Cytoplasm	Nucleoplasm Mitochondrion Cytosol Calcineurin Complex Sarcolemma
	Molecular Function	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Nuclear Localization Sequence Binding Calcium-dependent Protein Binding	Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Cyclosporin A Binding Phosphatase Binding Protein Domain Specific Binding
	Biological Process	Visual Perception Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Response To Stimulus	Protein Dephosphorylation Wnt Signaling Pathway, Calcium Modulating Pathway Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation
Drugs			Myristic acid Voclosporin
Diseases
GWAS		C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronotype ( 30696823) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 33536424)	General cognitive ability ( 29844566) Height ( 25282103) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)
Interacting Genes		9 interacting genes: CACNA1A CACNA1C CSNK2A2 FOS GRK5 ITPR1 ITPR3 NMT1 PPP3R1	10 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC
Entrez ID		9478	5534
HPRD ID		12025	03195
Ensembl ID		ENSG00000157782	ENSG00000221823
Uniprot IDs		Q9NZU7	P63098
PDB IDs		2K7B 2K7C 2K7D 2LAN 2LAP 3OX5 3OX6	1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU
Enriched GO Terms of Interacting Partners?
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