EIF4E2 and CAB39

Data Source:
BioGRID (genetic interference)

		EIF4E2	CAB39
Description		eukaryotic translation initiation factor 4E family member 2	calcium binding protein 39
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GO Annotations	Cellular Component	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex	Extracellular Region Cytosol Membrane Z Disc Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Cell Cycle Arrest Signal Transduction Positive Regulation Of Peptidyl-threonine Phosphorylation Response To Activity Peptidyl-serine Phosphorylation Activation Of Protein Kinase Activity Intracellular Signal Transduction Neutrophil Degranulation Cellular Hypotonic Response Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways		ISG15 antiviral mechanism	Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)
Interacting Genes		45 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	12 interacting genes: CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB
Entrez ID		9470	51719
HPRD ID		05798	10091
Ensembl ID		ENSG00000135930	ENSG00000135932
Uniprot IDs		B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1	A0A024R496 Q9Y376
PDB IDs		2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN	1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27
Enriched GO Terms of Interacting Partners?
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