CD34 and CHST4

Data Source:
HPRD (in vitro)

		CD34	CHST4
Description		CD34 molecule	carbohydrate sulfotransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Basal Plasma Membrane Apical Plasma Membrane Glomerular Endothelium Fenestra Intercellular Bridge Perinuclear Region Of Cytoplasm	Golgi Membrane Trans-Golgi Network Integral Component Of Membrane Intrinsic Component Of Golgi Membrane
	Molecular Function	Protein Binding Transcription Factor Binding Carbohydrate Binding Sulfate Binding	N-acetylglucosamine 6-O-sulfotransferase Activity Sulfotransferase Activity
	Biological Process	Tissue Homeostasis Endothelial Cell Proliferation Glomerular Filtration Endothelium Development Cell-matrix Adhesion Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Hemopoiesis Negative Regulation Of Blood Coagulation Negative Regulation Of Interleukin-2 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-10 Production Mesangial Cell-matrix Adhesion Paracrine Signaling Positive Regulation Of Odontogenesis Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Angiogenesis Cell Motility Regulation Of Immune Response Leukocyte Migration Transdifferentiation Vascular Wound Healing Hematopoietic Stem Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Granulocyte Colony-stimulating Factor Production Extracellular Exosome Assembly Glomerular Endothelium Development Stem Cell Proliferation Metanephric Glomerular Mesangial Cell Differentiation Cell-cell Adhesion Negative Regulation Of Cellular Response To Heat Negative Regulation Of Cellular Response To Hypoxia Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Death Positive Regulation Of Vasculogenesis	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process Protein Sulfation Sulfur Compound Metabolic Process Inflammatory Response Immune Response Cell Adhesion Cell-cell Signaling O-glycan Processing
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age-related macular degeneration ( 23326517) Automobile speeding propensity ( 30643258) Drug experimentation measurement ( 30718321) Estimated glomerular filtration rate ( 31152163) Febrile seizures (MMR vaccine-related) ( 25344690) General risk tolerance (MTAG) ( 30643258) Heart rate ( 23583979) Refractive error ( 32231278) Resting heart rate ( 27798624 20639392) RR interval (heart rate) ( 30679814) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: AGR2 CHST4 CRKL PRKCD	2 interacting genes: CD34 DCPS
Entrez ID		947	10164
HPRD ID		00790	07477
Ensembl ID		ENSG00000174059	ENSG00000140835
Uniprot IDs		P28906	Q8NCG5
PDB IDs
Enriched GO Terms of Interacting Partners?
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