LY86 and CD180

Data Source:
HPRD (in vivo, in vitro)

		LY86	CD180
Description		lymphocyte antigen 86	CD180 molecule
Image
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response	B Cell Proliferation Involved In Immune Response Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways		Toll Like Receptor 4 (TLR4) Cascade	Toll Like Receptor 4 (TLR4) Cascade
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412) Lung function (FEV1/FVC) ( 30804560) Major depressive disorder (broad) ( 20038947) Multiple sclerosis ( 31604244) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum uric acid levels ( 30993211) Urate levels in overweight individuals ( 25811787) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 27918534) Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI ( 27918534) Waist-hip ratio ( 23563607 23966867 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Common carotid intima-media thickness in HIV infection ( 29206233) General cognitive ability ( 29844566) Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		3 interacting genes: APP CD180 GEMIN4	1 interacting genes: LY86
Entrez ID		9450	4064
HPRD ID		05578	03749
Ensembl ID		ENSG00000112799	ENSG00000134061
Uniprot IDs		O95711	Q99467
PDB IDs		3B2D	3B2D
Enriched GO Terms of Interacting Partners?
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