CD180 and LY86

Data Source:
HPRD (in vivo, in vitro)

		CD180	LY86
Description		CD180 molecule	lymphocyte antigen 86
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix	Extracellular Space
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	B Cell Proliferation Involved In Immune Response Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Cellular Response To Lipopolysaccharide	Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response
Pathways		Toll Like Receptor 4 (TLR4) Cascade	Toll Like Receptor 4 (TLR4) Cascade
Drugs
Diseases
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233) General cognitive ability ( 29844566) Gut microbiota (bacterial taxa) ( 27723756)	Chronic obstructive pulmonary disease ( 30804561) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412) Lung function (FEV1/FVC) ( 30804560) Major depressive disorder (broad) ( 20038947) Multiple sclerosis ( 31604244) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum uric acid levels ( 30993211) Urate levels in overweight individuals ( 25811787) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 27918534) Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI ( 27918534) Waist-hip ratio ( 23563607 23966867 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		1 interacting genes: LY86	3 interacting genes: APP CD180 GEMIN4
Entrez ID		4064	9450
HPRD ID		03749	05578
Ensembl ID		ENSG00000134061	ENSG00000112799
Uniprot IDs		Q99467	O95711
PDB IDs		3B2D	3B2D
Enriched GO Terms of Interacting Partners?
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