MUC16 and SUN2

Data Source:
BioGRID (proximity labelling technology)

		MUC16	SUN2
Description		mucin 16, cell surface associated	Sad1 and UNC84 domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Vesicle Extracellular Exosome	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Cell Adhesion O-glycan Processing	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Meiotic synapsis
Drugs		Oregovomab
Diseases
GWAS		Asthma ( 30929738 32296059) Hepcidin/transferrin saturation ratio ( 27846281) Serum cancer antigen 125 levels ( 31666285) Tourette syndrome ( 30818990)	Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		3 interacting genes: LGALS1 MSLN UBC	4 interacting genes: HGS NRM RAB5B RPS20
Entrez ID		94025	25777
HPRD ID		07548	15611
Ensembl ID		ENSG00000181143	ENSG00000100242
Uniprot IDs		B3KY81 Q8WXI7	A0A024R1P7 B4E2A6 Q9UH99
PDB IDs			3UNP 4DXR 4DXS 4DXT 4FI9
Enriched GO Terms of Interacting Partners?
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