MUC16 and LGALS1

Data Source:
HPRD (in vivo, in vitro)

		MUC16	LGALS1
Description		mucin 16, cell surface associated	galectin 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Vesicle Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Cell Adhesion O-glycan Processing	Plasma Cell Differentiation Apoptotic Process Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Response To Drug Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Cellular Protein Metabolic Process Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Oregovomab	Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol
Diseases
GWAS		Asthma ( 30929738 32296059) Hepcidin/transferrin saturation ratio ( 27846281) Serum cancer antigen 125 levels ( 31666285) Tourette syndrome ( 30818990)	Fat distribution (HIV) ( 21897333)
Interacting Genes		3 interacting genes: LGALS1 MSLN UBC	17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1
Entrez ID		94025	3956
HPRD ID		07548	01040
Ensembl ID		ENSG00000181143	ENSG00000100097
Uniprot IDs		B3KY81 Q8WXI7	A0A384MR27 P09382
PDB IDs			1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?