CPNE6 and LAMTOR3

Data Source:
BioGRID (two hybrid)

		CPNE6	LAMTOR3
Description		copine 6	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Axon Dendrite Perikaryon Synapse Clathrin-coated Endocytic Vesicle Extracellular Exosome	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ragulator Complex
	Molecular Function	Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Activator Activity Molecular Adaptor Activity
	Biological Process	Lipid Metabolic Process Chemical Synaptic Transmission Nervous System Development Vesicle-mediated Transport Cell Differentiation Glycerophospholipid Biosynthetic Process Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension	MAPK Cascade Activation Of MAPKK Activity Cell Cycle Arrest Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Cellular Protein Localization Neutrophil Degranulation Cellular Response To Amino Acid Stimulus Protein Localization To Cell Junction
Pathways		Glycerophospholipid biosynthesis	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Triglyceride levels ( 32203549)	Mean reticulocyte volume ( 32888494)
Interacting Genes		14 interacting genes: AGR2 AK5 ANXA7 CDKN1A GRB7 LAMTOR3 MAPK11 MEOX2 NOTCH3 OS9 PIN1 SMN1 TK1 TTR	20 interacting genes: ADAMTS10 APOL6 BHMT CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS1 SUFU TFE3 TGM7 UBR1 ZSCAN4
Entrez ID		9362	8649
HPRD ID		05748	04485
Ensembl ID		ENSG00000100884	ENSG00000109270
Uniprot IDs		B3KWK1 O95741	Q9UHA4
PDB IDs			1SKO 2ZL1 3CPT 5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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